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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYAR
All Species:
24.55
Human Site:
T280
Identified Species:
38.57
UniProt:
Q9NX58
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX58
NP_001139197.1
379
43615
T280
R
R
H
S
E
V
E
T
D
S
K
K
K
K
M
Chimpanzee
Pan troglodytes
XP_001153728
379
43666
T280
R
R
H
S
E
V
E
T
D
S
K
K
K
K
M
Rhesus Macaque
Macaca mulatta
XP_001096675
379
43478
T280
R
K
H
S
E
V
E
T
D
S
K
K
K
K
M
Dog
Lupus familis
XP_536242
380
42964
I281
Q
K
H
S
E
D
D
I
E
S
K
K
K
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q08288
388
43717
S289
P
K
H
S
G
A
E
S
G
Y
K
K
K
K
M
Rat
Rattus norvegicus
Q6AYK5
386
43662
S287
Q
K
H
S
E
V
E
S
D
N
K
K
K
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511111
391
45222
T291
R
K
P
S
E
N
E
T
T
S
K
K
K
K
M
Chicken
Gallus gallus
XP_420792
364
42082
P261
H
K
H
I
E
E
E
P
C
I
T
K
K
K
M
Frog
Xenopus laevis
NP_001086609
360
41600
D241
K
K
H
A
E
D
E
D
E
N
D
S
E
G
Q
Zebra Danio
Brachydanio rerio
NP_956973
320
37238
E234
S
L
N
E
E
G
E
E
P
D
N
Q
E
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610573
281
32090
G204
A
A
E
E
T
S
N
G
V
T
S
D
F
D
W
Honey Bee
Apis mellifera
XP_623803
246
28455
I169
N
G
K
M
S
E
K
I
N
N
V
Q
D
T
N
Nematode Worm
Caenorhab. elegans
Q09464
253
28497
T176
K
E
T
T
V
A
T
T
A
A
E
V
T
D
A
Sea Urchin
Strong. purpuratus
XP_780603
1141
125640
T457
K
R
D
K
D
I
D
T
V
I
V
N
K
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37263
153
17720
K76
Q
K
Q
K
Q
Q
Q
K
Q
Q
Q
K
Q
H
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
97.3
76.8
N.A.
72.6
74.8
N.A.
62.9
55.6
53.2
43.7
N.A.
27.1
26.9
29.8
20.2
Protein Similarity:
100
98.9
98.6
85.5
N.A.
83.5
86.5
N.A.
76.2
71.7
69.9
64.3
N.A.
46.9
40.1
44.8
28.1
P-Site Identity:
100
100
93.3
53.3
N.A.
53.3
73.3
N.A.
73.3
46.6
20
13.3
N.A.
0
0
6.6
26.6
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
100
N.A.
80
53.3
60
33.3
N.A.
6.6
26.6
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
0
14
0
0
7
7
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
7
14
14
7
27
7
7
7
7
14
0
% D
% Glu:
0
7
7
14
60
14
60
7
14
0
7
0
14
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
7
0
0
7
7
0
7
7
0
0
0
0
7
0
% G
% His:
7
0
54
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
7
0
7
0
14
0
14
0
0
0
0
0
% I
% Lys:
20
54
7
14
0
0
7
7
0
0
47
60
60
60
0
% K
% Leu:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
47
% M
% Asn:
7
0
7
0
0
7
7
0
7
20
7
7
0
0
7
% N
% Pro:
7
0
7
0
0
0
0
7
7
0
0
0
0
0
0
% P
% Gln:
20
0
7
0
7
7
7
0
7
7
7
14
7
0
14
% Q
% Arg:
27
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
47
7
7
0
14
0
34
7
7
0
0
0
% S
% Thr:
0
0
7
7
7
0
7
40
7
7
7
0
7
14
0
% T
% Val:
0
0
0
0
7
27
0
0
14
0
14
7
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _